bioinformatics相关论文
目的:应用生物信息学方法筛选和分析非酒精性脂肪性肝病（NAFLD）特征差异表达关键基因。方法:GEO数据库中下载NAFLD相关的表达矩阵GSE......
Genomic reassortment is an important evolutionary mechanism for influenza viruses.In this process,the novel viruses acqu......
Objective: To investigate the core target genes of miR-29b-3p, and analyze the clinical significance of the core target ......
Towards a comprehensive understanding of p75 neurotrophin receptor functions and interactions in the
The role of neurotrophins in neuronal plasticity has recently become a strong focus inneuroregeneration research field t......
Circular RNAs (circRNAs) are a new and large group of non-coding RNA molecules that are abundantly expressed in the cent......
MicroRNAs are small non-coding RNAs that play crucial roles in the regulation of gene expression and protein synthesis d......
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Dynamic model prediction of digestible energy content across feed ingredients using biostatistics an
The Biostatistics and Bioinformatics approach is becoming increasingly important in pattern recognition and dynamic mode......
An EST-based search followed by molecular identification for potential antimicrobial peptides in the
Brassicanapuswas the third leading source of vegetable oil in the world after only soya bean and oil palm.The developmen......
microRNAs(miRNAs)are a class of non-coding small RNAs which can negetively regulate their target messeager RNAs(mRNAs)at......
Beef cattle feeding has great differences between North and South China, with corn silage and hay based diet in North, a......
Identifying hub genes response to IL-β stimuli in disc degeneration based on gene expression profili
Objective To screen differentially expressed genes (DEGs) affected by IL-1β in human disc tissue samples obtained from ......
Analysis of differentially methylated expressed genes and pathways in lung adenocarcinoma based on b
目的 The aim of this study was to identify methylated-differentially expressed genes in LUAD and explore pathways throug......
Excavating and conducting function analysis of hub genes of esophageal carcinoma by integrated bioin
Objective To gain critical genes about esophageal carcinoma by referring to public microarray databases and to investiga......
Objective Growing evidence has shed light on that the differential expression of histone deacetylases(HDACs)might be a p......
Bioinformatics analysis of differentially expressed miRNArelated mRNAs and their prognostic value in
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Objective Nasopharyngeal carcinoma(NPC)is an invasive cancer with particularly high incidence in Southeast Asia and Sout......
目的 ToestablishTcellrepertoiredatabaseofinfluenzaA(H7N9)virusinfectedconvalecentpatientsandidentifythespecific changesi......
ITGB1,SERPINH1 and SPARC as novel diagnostic and prognostic biomarkers in pancreatic cancer identifi
Objective Background: Pancreatic cancer is one of the most lethal cancers in modern society,with high potential to metas......
Identification of key pathways and genes of survival in gastric cancer based on bioinformatics analy
Objective Gastric cancer is the fifth most common malignancy in the world and continues to carry a very poor prognosis.T......
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RoleofDysregulatedCOL3A1andRPL8,RPS16,RPS23inDiscDegenerationRevealedbyBioinformaticsM
Background:Discdegeneration(DD)isoneofthemaincausesoflowbackpain,whichhasbecomeanenormouseconomicburdenforsociety.Purpos......
The Effect of Delayed Motherhood on MicroRNA and LncRNA Regulation of Gene Expression:a Predictive B
To date,there are no published reports of the profile of microRNA(miRNA),long non-coding RNA(lncRNA)and messenger RNA(mR......
The bioinformaticsanalyses reveal novel antigen epitopesin Major Outer Membrane Protein (MOMP) of Ch
Purpose: The aim of this study was to predict the T-cell and B-cell epitopes in Major Outer Membrane Protein (MOMP) ofCh......
A MAPKK kinase gene was firstly cloned from Dunaliela salina by RT-PCR and RACE technology.The full length of cDNA for M......
PanGU: An Automatic Pipeline for Comprehensive Optimization of Prokaryotic Genome Annotation Through
With the rapid development of genome sequencing technologies,large amounts of microbial genomes have been sequenced inex......
Some pseudogenes have been reported to play important roles in gene regulation,but little is known about the evolutionar......
Nucleosome has been a extensively studied topic not only because its position affects directly cellular processes,such a......
Background: Since biological data are usually complex and high dimensional,selecting meaningful information from the bio......
Pancreatic beta cell dysfunction is a central role of developmemt of type 2 diabetes[1].And the chronic dislipidemia (li......
Cloning, expression and bioinformatics analysis of heavy metal resistance gene afe_1862 from Acidith
Biological cells form different defense systems for metal ions,such as repulsion,regionalization,or synthesis of metal-b......
Comparative Proteomics-Based Molecular Network Analyze Reveal Spactio-Temporal Protein Dynamics of R
Spermatogenesis in mammalian is a complex yet tightly regulated developmental process that consists of three principal s......
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Microbial species in water ecological environment is very large,some of it will be the Potential pathogenic factor for a......
Erythropoiesis is the process by which hematopoietic stem cells proliferate and differentiate through multiple stages to......
Tremendous differences between human sexes are universally observed and accepted.Women and men show big differences in a......
Toxoplasma ROP16 is crucial in the host-pathogen interaction by playing a role as a virulent factor during invasion.To g......
To explore mechanisms in obesity-associated asthma using functional proteomics technology: A pilot s
Rationale: Obesity-associated asthma exhibits different clinical features such as neutrophilic airway inflammation and p......
Exome sequencing revealed a novel splice donor mutation in disease gene of Duchenne muscular dystrop
Backgroud Duchenne muscular dystrophy is the most common and lethal X-linked neuromuscular diseases, which is characteri......
Electronic Cloning and Validating of the Subtractive Fragment of Human colorectal Adenocarcinoma cDN
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Summary: Small non-coding RNAs (sRNAs),including microRNA (miRNA),piwi-interaeting RNAs (piRNAs) and siRNA et al.,have a......
Bacterial pathogens secret numerous proteins,the effectors,in order to adapt to the new environment or promote virulence......
Chor et al found that tetrapods animals (including all mammals) the frequency distribution of k-mer is showing multiple ......
